Lithium diisopropylamide solution 2.0 M in THF/heptane/ethylbenzene

Stock code :361798
Brand :Sigma-Aldrich
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Lithium diisopropylamide solution 2.0 M in THF/heptane/ethylbenzene

Description

General description

Lithium diisopropylamide solution (LDA) is a sterically hindered non-nucleophilic strong base widely used in organic synthesis.[3]

Application

Lithium diisopropylamide solution (LDA) can be used:
• As an initiator in the anionic polymerization of D, L-lactide and methyl methacrylate.[3]
• To facilitate ester enolization.[4]
• To convert carboxylic acids to enediolate intermediates for preparing trifluoromethyl ketones.[5]
• In ortho-lithiation of arylsulfonyloxazolidinones to prepare N-substituted saccharin analogs.[6]
• To catalyze ortholithiation and Fries rearrangement of aryl carbamates.
• As a promoter in the isomerization of allylic ethers to (Z)-propenyl ethers.[7]

Packaging

4×25, 100, 4×100, 800 mL in Sure/Seal™

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