SMC™ Human Interleukin 2 (IL-2) Immunoassay Kit
Interleukin-2 (IL-2) is a naturally produced cytokine whose key function is to activate the immune system during an infectious attack. Foreign antigens trigger IL-2 secretion. When IL-2 binds to its receptor IL-2R, the complex stimulates immune cell proliferation and differentiation, including cytotoxic T-cells, natural killer cells, lymphocytes, monocytes and macrophages. Interestingly, research suggests that impaired IL-2 activity has been linked to the development of autoimmunity rather than immunodeficiency. Autoimmune system hyperactivity may cause chronic inflammatory disorders, lymphadenopathy, hepatomegaly and splenomegaly. Recent studies also suggest an important role for IL-2 in the regulation of innate immunity.
The SMC™ IL-2 Immunoassay Kit contains all reagents required to perform the assay. This assay takes advantage of a standard immunoassay workflow configured in a standard plate format. Assay protocols are similar to existing sandwich ELISA methods with two key differences: 1) Elution buffer disrupts the sandwich, separating the labeled detection antibody for quantification. 2) The SMC™ immunoassay system detects analytes using Single Molecule Counting (SMC™) technology.
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors
The sensitivity of Single Molecule Counting (SMC™) technology gives the SMC™ Human IL-2 Immunoassay Kit unparalled performance in the quantification of IL-2 in human EDTA plasma and serum.
Used to detect/quantify:IL-2
IL-2 Coated Beads
Standard Diluent
IL-2 Detection Antibody
Assay Buffer
Human IL-2 Standard
SMC™ Human IL-2 Immunoassay Kit Instructions
10X Wash Buffer
Elution Buffer B
Buffer D
Low-end CV% Range: 3 - 10%|Low-end CV% Average: 6%
SMC is a trademark of Singulex
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial
